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KMID : 0616120120430010085
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Korean Journal of Pharmacognosy
2012 Volume.43 No. 1 p.85 ~ p.93
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Screening of Antioxidative Activities and Antiinflammatory Activities in Local Native Plants
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Kim Han-Hyuk
Kwon Joo-Hee
Park Kwan-Hee
Kim Manh-Heun
Oh Myoeng-Hwan
Choe Kang-In
Jin Hye-Young
Kim Sung-Sik
Lee Min-Won
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Abstract
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181 kinds of local native plants were selected by its anti-inflammatorial folk medicinal uses and evaluated it antioxidative and inhibitory activity of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced 264.7 macrophage cells. Among the 181 kinds of plants, 99 species showed potent antioxidative activities and 20 extracts showed inhibitory activity towards nitric oxide production by more than 70% at a concentration of . Therefore, these plants should be considered promising candidates for the treatment of inflammatory diseases accompanying overproduction of NO.
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KEYWORD
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Local native plants, Antioxidative, Anti-inflammatory, DPPH, NBT/XO, Nitric oxide
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